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human total irs 1  (AMS Biotechnology)


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    AMS Biotechnology human total irs 1
    Human Total Irs 1, supplied by AMS Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+skin+total+rna/Human+Skin+Total+RNA/pmc12216818-70-30-33
    Average 96 stars, based on 3 article reviews
    human total irs 1 - by Bioz Stars, 2026-10
    96/100 stars

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    Article Title: KCNQ1 is an essential mediator of the sex-dependent perception of moderate cold temperatures
    Article Snippet: KCNQ1-5 specific primers used for PCR of human skin cDNA (human skin cDNA, ZYAGEN Catalog #: HD-101) were designed to span an intron.

    Expressing:

    Article Title: KCNQ1 is an essential mediator of the sex-dependent perception of moderate cold temperatures.
    Article Snippet: Despite extensive studies over the past decades to identify the mechanism of temperature sensation, there is still a lack of understanding of the molecular sensors involved in cold sensation.. We found that the voltagegated potassium channel KCNQ1 (Kv7.1), which forms together with KCNE1 the cardiac delayed rectifier potassium current IKs, is in addition to its known function in the heart, a highly relevant and sexspecific sensor of moderately cold temperatures.. Based on the newly identified functional expression in Cfibers, the substantial temperatureand mentholsensitivity, together with the strong in vivo effects on cold avoidance, we propose a novel extracardiac function for KCNQ1 channels, namely the perception of moderate/ambient cold temperatures in a sexdependent manner.

    Reverse Transcription:

    Article Title: KCNQ1 is an essential mediator of the sex-dependent perception of moderate cold temperatures.
    Article Snippet: Despite extensive studies over the past decades to identify the mechanism of temperature sensation, there is still a lack of understanding of the molecular sensors involved in cold sensation.. We found that the voltagegated potassium channel KCNQ1 (Kv7.1), which forms together with KCNE1 the cardiac delayed rectifier potassium current IKs, is in addition to its known function in the heart, a highly relevant and sexspecific sensor of moderately cold temperatures.. Based on the newly identified functional expression in Cfibers, the substantial temperatureand mentholsensitivity, together with the strong in vivo effects on cold avoidance, we propose a novel extracardiac function for KCNQ1 channels, namely the perception of moderate/ambient cold temperatures in a sexdependent manner.



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